Type XVIII Collagen Modulates Keratohyalin Granule Formation and Keratinization in Oral Mucosa
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چکیده
منابع مشابه
Type XVIII collagen degradation products in acute lung injury
INTRODUCTION In acute lung injury, repair of the damaged alveolar-capillary barrier is an essential part of recovery. Endostatin is a 20 to 28 kDa proteolytic fragment of the basement membrane collagen XVIII, which has been shown to inhibit angiogenesis via action on endothelial cells. We hypothesised that endostatin may have a role in inhibiting lung repair in patients with lung injury. The ai...
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Mice lacking type XVIII collagen have defects in the posterior part of the eye, including delayed regression of the hyaloid vasculature and poor outgrowth of the retinal vessels. We report here that these mice also have a fragile iris and develop atrophy of the ciliary body. The irises of Col18a1-/- mice can be seen to adhere to the lens and cornea. After the pupils begin to function, the doubl...
متن کاملType Xviii and Xv Collagens: Primary Structure of Human Alpha1(xviii) Chain, Phenotypic Studies of Type Xviii Collagen Single Null and Type Xviii and Xv Collagen Double Null Mice
In this thesis study, the primary structure of the human α1(XVIII) polypeptide was elucidated, its tissue distribution was studied, and the phenotypic changes in the mouse eye due to lack of type XVIII collagen in a knock-out mouse model were studied further. In addition, the consequences of simultaneous lack of both type XVIII and XV collagen were studied in a mouse model lacking both of these...
متن کاملCollagen fibril arrangement and size distribution in monkey oral mucosa.
Collagen fibre organisation and fibril size were studied in the buccal gingival and hard palate mucosa of Macacus rhesus monkey. Light and electron microscopy analysis showed connective papillae exhibiting a similar inner structure in the different areas examined, but varying in distribution, shape and size. Moving from the deep to surface layers of the buccal gingival mucosa (free and attached...
متن کاملAn Electron Microscopic Study on the Epithelium of the Rat Tongue.
There are available results of electron microscopic studies as. regards the oral mucosa by such researchers as Sognnaes and Albright (1956, 1958), Themann (1958), Fasske and Themann (1959), Frenkel (1959), Albright (1960), Rhodin and R eith (1962) and Arai (1961, 1962). But all of them fail to give a description of the epithelium of the tongue, and only Rhodin and R e i t h give a brief mention...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20194739